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Upcoming Seminar: Nils Birkholz

Posted by on 21 August 2023 | Comments

1:00 pm, Monday, 21 August
Room BIG13, Ground Floor
Biochemistry Building
710 Cumberland St

Nils Birkholz
Microbiology & Immunology

Diverse regulation strategies govern bacterial defence and phage counter-defence


Bacteria are under constant threat of attack by their viral predators, phages. This has led to the evolution of various bacterial defence systems, including restriction–modification and CRISPR–Cas. Phages in turn use counter-defences such as anti-CRISPR proteins to neutralise host defence. However, all this weaponry comes at a cost, necessitating tight control. In this seminar, I will present my research on the multi-layered, and sometimes unexpected, regulation strategies – transcriptional, post-transcriptional and epigenetic – that are involved in the deployment of bacterial defence and phage counter-defence.