Second Semester - 18 points
Disease mechanisms of key microbial pathogens, including bacteria, protozoa, and fungi. Treatment and control of microbial diseases. Role of the human microbiome and commensals in health and disease.
In this paper, we will discuss select microbes that cause important human diseases, the impact of commensal microbes on health, and strategies developed to prevent or treat infections.
This paper is relevant to students who have an interest in medical microbiology. It is not designed for medical students, but rather for potential microbiological researchers, managers of medical practices or medical laboratories, or future makers of medical policy.
The lectures are divided into four modules. There will be one tutorial.
Associate Professor Keith Ireton: Molecular approaches to identify bacterial virulence factors and host susceptibility factors; specific bacterial pathogens and their respective diseases
Dr Xochitl Morgan: The human microbiome; the tole of commensals in health and disease
Dr Bruce Russell: Parasitology
Dr James Ussher: Treatment of infections with antimicrobial agents; vaccines
The human body is home to thousands of bacterial species. Many are innocuous, but others may be pathogenic.
In the MICR332 labs, you will plan your own experiments, develop a research project, and prepare a written report of your findings. You will investigate your own microflora by isolating bacteria from different body sites. You will then identify and characterise the isolated bacterial strains. You will also identify and characterise two ‘unknown’ medically relevant strains that are given to you.
You will be using differential and selective agar for the cultivation of bacteria and also a variety of medical laboratory assays to test for the production of known bacterial virulence factors.
MICR221 and MICR223
Note: BBiomedSc students are permitted to take MICR332 without the MICR221 prerequisite.
Days and times: Wednesday, Friday 12:00 – 12:50 pm
Locations: Wednesdays: TG08; Fridays: ARCH1
Days and times: Tuesday 2:00 PM- 5:50 PM; Wednesday 9:00 AM -5:50 PM
Note: You will also need to perform small amounts of lab work on other days. Times at which the lab is available are given in the MICR 332 lab manual.
Location: 3rd floor microbiology laboratory, Microbiology building.
Attendance: Required in order to make terms.
Note: there are no lecture or practical clashes between any of the 300-level MICR papers
Recommended text: Wilson, BA., Salyers, AA., Whitt, DD. And Winkler ME. 2011, Third edition. Bacterial pathogenesis. A Molecular Approach. American Society for Microbiology.
Note: When appropriate, lecturers will suggest reading in the text that may help you better understand their lecture material. However, material for the exams will be taken from lecture content. Reading the text is suggested, but not absolutely required.
View the details of this paper on the University of Otago website
For further information on this paper, please contact Keith Ireton (+64 3 479 7396, keith.ireton@otago.ac.nz).
For more information on this course, please contact Associate Professor Keith Ireton.
