First Semester - 18 points
Fundamental concepts in microbiology, building from the characteristics of microorganisms, through the handling and containment of microorganisms, to medical microbiology and immunology.
MICR 221 is a 32-lecture course that gives you a general introduction to Microbiology and Immunology. Lectures cover the following areas:
1. Physical and chemical requirements of microbial growth
2. Bacterial nutrition
3. The two sides of bacterial endospores
4. Physical control methods
5. Chemical control methods
6. Bacterial persistence and surviving an environment in flux
7. The balance of anabolic and catabolic reactions
8. Principles of bacterial aerobic cellular respiration
9. Respiration without oxygen
10. Bacterial ATP synthesis and how it became the newest target-space for antibiotics
11. Introduction to the immune system
12. Antigen recognition
13. The major histocompatibility complex (MHC)
14. Antigen presentation and costimulation
15. T cells
16. B cells
17. Effector cells and immune tolerance
18. Introduction to viruses: what are they and what is their composition?
19. Viruses and their hosts: the organisms viruses infect and the virus life cycle in a host cell
20. Virus multiplication I: the replication of viruses with DNA genome
21. Virus multiplication II: the replication of viruses with RNA genome
22. Viruses and diseases: types of viral infections and human diseases viruses cause
23. Virus emergence, evolution, and classification: where do new viruses come from and how are they classified?
24. Virus prevention and control: antiviral drugs and vaccines
26. Impact of symbiosis on human health and disease
27. Impact of microbe, host, and medicine on disease
28. Food-borne diseases
29. Respiratory infections
30. Sexually transmitted diseases
31. Microbial virulence factors and their host targets
The MICR 221 paper includes a 6-lab course. The labs aim to teach you fundamental laboratory skills and reinforce concepts discussed in lectures. You will learn basic bacterial culture techniques, how to grow bacteria, how to estimate bacterial numbers and how to identify bacteria. You will gain microscope and staining skills and visualise microbes using the microscope. The labs will also see you look at medically important microbes, including a look at the bacteria on your own skin and a look at pharmaceutical products that can be used to control microbial infections. The labs will cover eukaryotic microbes such as fungi, protozoa and algae.
The MICR 221 lab course covers:
CELS 191; CHEM 191 or CHEM 111; 36 further 100-level points
Prescott's Microbiology by Willey, Sandman and Wood, 12th edition, 2023, McGraw-Hill Publishers
Kuby Immunology, 8th edition (2019), Palgrave Macmillan. Note, Kuby Immunology is also the recommended text for those wishing to continue immunology in MICR334.
View the details of this paper on the University of Otago website
Students are encouraged to contact staff by email to make arrangements for a time to discuss course-related matters.
For more information on this course, please contact Dr Judith Bateup.