Monday 14 October, 1:00pm
Biochemistry Seminar Room BIG13
Prof Parry Guilford
Dept of Biochemistry
Hereditary Diffuse Gastric Cancer: the evolution of a cancer syndrome
Hereditary Diffuse Gastric Cancer (HDGC) is a cancer syndrome caused largely by germline mutations in the CDH1 gene. Its clinical management requires finding a difficult balance between prophylactic surgery and endoscopic surveillance. In this talk I will outline how our understanding of HDGC has changed as more affected families have been identified and describe our progress towards developing drugs for the chemoprevention of this syndrome.
Monday 14 October, 1:00pm · Biochemistry Seminar Room BIG13
