My research focus is on genetic engineering of T cells and antibody engineering for solid tumour immunotherapy.
Black, L. V. C., Saunderson, S. C., Coutinho, F. P., Muhsin-Sharafaldine, M.-R., Damani, T. T., Dunn, A. C., & McLellan, A. D. (2016). The CD169 sialoadhesin molecule mediates cytotoxic T-cell responses to tumour apoptotic vesicles. Immunology & Cell Biology, 94, 430-438. doi: 10.1038/icb.2015.111
Muhsin-Sharafaldine, M.-R., Saunderson, S. C., Dunn, A. C., Faed, J. M., Kleffmann, T., & McLellan, A. D. (2016). Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles. Oncotarget, 7(35), 56279-56294. doi: 10.18632/oncotarget.10783
Saunderson, S. C., Dunn, A. C., Crocker, P. R., & McLellan, A. D. (2014). CD169 mediates the capture of exosomes in spleen and lymph node. Blood, 13(2), 208-216. doi: 10.1182/blood-2013-03-489732
Bouwer, A. L., Saunderson, S. C., Caldwell, F. J., Damani, T. T., Pelham, S. J., Dunn, A. C., Jack, R. W., … McLellan, A. D. (2014). NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge. Journal of Immunology, 192(5), 2514-2521. doi: 10.4049/jimmunol.1202797
Bouwer, A. L., Saunderson, S. C., Dunn, A. C., Lester, K. L., Crowley, L. R., Jack, R. W., & McLellan, A. D. (2013). Rapid interferon-gamma release from natural killer cells induced by a streptococcal commensal. Journal of Interferon & Cytokine Research, 33(8), 459-466. doi: 10.1089/jir.2012.0116
Saunderson, S. C., Schuberth, P. C., Dunn, A. C., Miller, L., Hock, B. D., MacKay, P. A., … Jack, R. W., & McLellan, A. D. (2008). Induction of exosome release in primary B cells stimulated via CD40 and the IL-4 receptor. Journal of Immunology, 180(12), 8146-8152.
