1:00 pm, Monday, 3 July
Room BIG13, Ground Floor
Biochemistry Building
710 Cumberland St
Prof Iain Lamont
Biochemistry
Genetic basis of antibiotic resistance in Pseudomonas aeruginosa
The opportunistic pathogen Pseudomonas aeruginosa is a frequent cause of acute life-threatening infections in patients with predisposing conditions, and of chronic infections in individuals with cystic fibrosis and other lung diseases. These bacteria can rapidly become antibiotic resistant and the frequency of isolates resistant to multiple antibiotics has led the World Health Organisation to list P. aeruginosa as one of the three bacterial species for which new treatments are most urgently needed. Resistance can arise through mutations that reduce the effectiveness of antibiotics, or by acquisition of genes that cause antibiotics to be inactivated. This talk will outline two recent studies from our lab that serve as case studies to illustrate these processes.
