Associate Professor Alexander McLellan
+64 (3) 479-7728
Applied and Molecular Immunology, Cancer Immunobiology
Year of Appointment
BSc, MSc (Canterbury) PhD (Otago)
A central theme of the laboratory is the study of the cells and the molecules involved in antigen presentation during immune responses to infection, cancer and allogeneic transplants. We have made contributions to the field of cellular adhesion and costimulation, as well to our understanding of the different roles of dendritic cell subsets in the immune response. A recent focus has been the biology of soluble MHC molecules, especially as diagnostic markers for renal transplant rejection, but also for their role as integral membrane proteins of exosomes.