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Microbiology Logo Microbiology & Immunology
Te Tari Moromoroiti me te Ārai Mate

Dr Hannah Hampton


Current research:

  • Understanding how bacteria regulate the expression of their CRISPR-Cas adaptive immune systems.
  •  Understanding the mode of action of abortive infection and toxin antitoxin ‘innate immune systems’. 
  • Exploring all innate and adaptive genome defences in Serratia

Links

Google Scholar https://scholar.google.com/citations?user=ZQwgLegAAAAJ&hi=en

Postgraduate Student (co)-supervision:

PhD

David Mayo Muñoz

Masters

Zacharie Paquet

 

Publications:

2020 Hampton, H.G, * Watson, B.N.J.* and Fineran, P.C. (2020). The arms race between bacteria and their phage foes Nature. 577. 327-336

2019 Hampton, H.G.,* Patterson, A.G., Chang, J.T., Taylor, C. and Fineran, P.C. (2019). GalK limits type I-F CRISPR-Cas expression in a CRP-dependent manner. FEMS Microbiology Letters. 366, 11, fnz137

2018 Hampton, H.G., Jackson, S.S., Fagerlund, R.D., Vogel, A.I.M., Dy, R.L., Blower, T.R. and Fineran, P.C. (2018). AbiE binfd cooperatively to the Type IV abiE toxin-antitoxin operator via a positively-charged surface and causes DNA bending and negative autoregulation. Journal of Molecular Biology. 430:1141-1156

2016 Hampton, H.G., McNeil, M.B., Patterson, T.J., Ney, B., Williamson, N. R., Easingwood, R.A., Bostina, M., Salmond, G.P.C and Fineran, P.C (2016). CRISPR-Cas gene editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia. Microbiology. 162. 1047-1058.

2014 McNeil, M.B., Hampton, H.G., Hards, K.J., Watson, B.N.J., Cook, G.M. and Fineran P.C. (2014). The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria. FEBS Letters. 588. 514-521.