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Microbiology Logo Microbiology & Immunology
Te Tari Moromoroiti me te Ārai Mate

Dr Laura Burga


Publications:

McCarthy, C., Jayawardena, N., Burga, L. N., & Bostina, M. (2019). Developing picornaviruses for cancer therapy. Cancers11(5), 685.  doi: 10.3390/cancers11050685

Jayawardena, N., Burga, L. N., Easingwood, R. A., Takizawa, K., Wolf, M., & Bostina, M. (2018). Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus. PNAS115(46), E10934-E10940.  doi: 10.1073/pnas.1810664115

Strauss, M., Jayawardena, N., Sun, E., Easingwood, R. A., Burga, L. N., & Bostina, M. (2018). Cryo-electron microscopy structure of Seneca Valley Virus procapsid. Journal of Virology92(6), e01927-17.  doi: 10.1128/jvi.01927-17

Miles, L. A., Burga, L. N., Gardner, E. E., Bostina, M., Poirier, J. T., & Rudin, C. M. (2017). Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus. Journal of Clinical Investigation127(8), 2957-2967.  doi: 10.1172/jci93472

Israelsen, W. J., Dayton, T. L., Davidson, S. M., Fiske, B. P., Hosios, A. M., Bellinger, G., … Burga, L. N., … Vander Heiden, M. G. (2013). PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells. Cell155, 397-409.  doi: 10.1016/j.cell.2013.09.025

Juvekar, A., Burga, L. N., Hu, H., Lunsford, E. P., Ibrahim, Y. H., Balmaña, J., … Wulf, G. M. (2012). Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer. Cancer Discovery2(11), 1048-1063.  doi: 10.1158/2159-8290.CD-11-0336

Burga, L. N., Hu, H., Juvekar, A., Tung, N. M., Troyan, S. L., Hofstatter, E. W., & Wulf, G. M. (2011). Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice. Breast Cancer Research13, R30.  doi: 10.1186/bcr2850

Yuan, T. L., Wulf, G., Burga, L., & Cantley, L. C. (2011). Cell-to-cell variability in PI3K protein level regulates PI3K-AKT pathway activity in cell populations. Current Biology21(3), 173-183.  doi: 10.1016/j.cub.2010.12.047

Burga, L. N., Tung, N. M., Troyan, S. L., Bostina, M., Konstantinopoulos, P. A., Fountzilas, H., … Wulf, G. M. (2009). Altered proliferation and differentiation properties of primary mammary epithelial cells from BRCA1 mutation carriers. Cancer Research69(4), 1273-1278.  doi: 10.1158/0008-5472.can-08-2954

Lam, P. B., Burga, L. N., Wu, B. P., Hofstatter, E. W., Lu, K. P., & Wulf, G. M. (2008). Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability. Molecular Cancer7, 91.  doi: 10.1186/1476-4598-7-91

Burga, L., Wellmann, F., Lukačin, R., Witte, S., Schwab, W., Schröder, J., & Matern, U. (2005). Unusual pseudosubstrate specificity of a novel 3,5-dimethoxyphenol O-methyltransferase cloned from Ruta graveolens L. Archives of Biochemistry & Biophysics440(1), 54-64.  doi: 10.1016/j.abb.2005.05.026