Our laboratory is focused on the following fundamental and applied aspects of ATP synthase biology:
1. Determining how the membrane-bound F-type ATP synthase has been adapted to function under different environments
• The model for these studies is the F-type ATP synthases from the polyextremophiles: Caldalkalibacillus thermarum strain TA2.A1, Clostridium paradoxum and Natranaerobius thermophilus
2. Identification and characterization of the molecular and structural mechanisms that regulate the activity and assembly of F-type ATP synthases
• The model for these studies is the F-type ATP synthases from Caldalkalibacillus thermarum strain TA2.A1 and E. coli
3. Methanogen ATP synthases as targets to control methane production in the rumen
• Identification of new inhibitors that target the A-type ATP synthase
• High throughout screening to identify inhibitors of methanogen growth
Please enquire to obtain more specific information on these projects: Gregory.cook@otago.ac.nz
Group members
Dr Falk Kalamorz
Postdoctoral Fellow
falk.kalamorz@otago.ac.nz
+64 3 479-7733
Marina Iglesias Cans
PhD student
miglesiascans@gmail.com
+64 3 479-8373
Marion Weimar, marion.weimar@otago.ac.nz, Research Technician
Jessica Petri, Summer student, jessi@kleinvolk.de